USP Grade 90% Purity Chondroitin Sulfate Ingredients Good for Joint Health
Chondroitin sulfate (CS) is widely distributed in the extracellular matrix and cell surface of animal tissues, and is formed by D-glucuronic acid and N-acetyl-D-amino galactose linked by 1,3 glycosidic bond to form disose, which is linked by β -1,4 glycosidic bond.
1. Physical properties: Chondroitin sulfate is an acid mucopolysaccharide substance extracted from animal tissue. It is generally white or white-like powder, odorless and soluble in water. The salts of chondroitin sulfate are relatively stable to heat and are not destroyed by heat up to 80℃.
2. Chemical properties: The degradation degree of chondroitin sulfate under acid, alkaline and enzymatic conditions can be expressed by the UV absorbance value, the greater the degradation degree, the greater the UV absorbance value. Moreover, the aqueous solution of chondroitin sulfate is unstable at higher temperatures or acidic environments, mainly undergoing deacetylation or degradation into monosaccharides or polysaccharides with small molecular weight.
3. Biological activity: Chondroitin sulfate has a variety of biological activities, including anti-inflammatory, immune regulation, cardiovascular and cerebrovascular protection, neuroprotection, anti-oxidation, cell adhesion regulation and anti-tumor effects. These activities make chondroitin sulfate a wide application in the medical field.
4. Medical care application: In Europe, the United States, Japan and other countries, chondroitin sulfate is mainly used as health food or drugs for the prevention and treatment of cardiovascular and cerebrovascular diseases, osteoarthritis, neuroprotection, etc. Clinically, chondroitin sulfate is often used in the treatment and prevention of arthritis, keratitis, chronic hepatitis, chronic nephritis, streptomycin-induced auditory disorders and other diseases.
| Product Name | Bovine Chondroitin Sulfate |
| Origin | Bovine Origin |
| Quality Standard | USP40 Standard |
| Appearance | White to off white powder |
| CAS Number | 9082-07-9 |
| Production process | enzymatic hydrolysis process |
| Protein Content | ≥ 90% by CPC |
| Loss on Drying | ≤10% |
| Protein Content | ≤6.0% |
| Function | Joint health Support, Cartilage and Bone Health |
| Application | Dietary supplements in Tablet, Capsules, or Powder |
| Halal Certificate | Yes, Halal Verified |
| GMP Status | NSF-GMP |
| Health Certificate | Yes, Health certificate is available for custom clearance purpose |
| Shelf Life | 24 months from production date |
| Packing | 25KG/Drum, Inner Packing: Double PE BAGS, Outer Packing: Paper Drum |
1. Animal tissue extraction: Chondroitin sulfate can be extracted from the cartilage tissue of pigs, cattle and other animals, such as the laryngeal bone, nasal middle bone and trachea of pigs. These cartilage tissues after a certain treatment process, can be extracted to obtain chondroitin sulfate.
2. Source of Marine life: Marine life is also one of the most important sources of chondroitin sulfate. For example, the cartilage of Marine organisms such as sharks, whales and crab shells is rich in chondroitin sulfate.
Note that chondroitin sulfate from different sources may differ in composition, structure, and activity. Therefore, in practical applications, appropriate chondroitin sulfate sources are selected according to the specific needs and uses. At the same time, in order to ensure the quality and safety of products, we should select regular manufacturers and suppliers, and follow the relevant regulations and standards.
3. Microbial fermentation: In recent years, with the development of biotechnology, the production of chondroitin sulfate by microbial fermentation has also become a new trend. Some specific microorganisms are able to synthesize chondroitin sulfate or its analogues under specific culture conditions. This method has the advantages of short production cycle, high yield and low cost, so it has a certain application prospect in industrial production.
4. Chemical synthesis: Although chondroitin sulfate mainly comes from natural extraction, chemical synthesis is also a possible way of production. Through chemical synthesis, the structure and purity of chondroitin sulfate can be precisely controlled, resulting in high-quality products. However, chemical synthesis is relatively rare in practical applications due to its complex, costly process and possible environmental problems.
| ITEM | SPECIFICATION | TESTING METHOD |
| Appearance | Off-white crystalline powder | Visual |
| Identification | The sample confirm with the reference library | By NIR Spectrometer |
| The infrared absorption spectrum of the sample should exhibit maxima only at the same wavelengths as that of chondroitin sulfate sodium WS | By FTIR Spectrometer | |
| Disaccharides composition: The ratio of the peak response to the△DI-4S to the △DI-6S is no less than 1.0 | Enzymatic HPLC | |
| Optical Rotation: Meet the requirements for optical rotation, specific rotation in specific tests | USP781S | |
| Assay(Odb) | 90%-105% | HPLC |
| Loss On Drying | < 12% | USP731 |
| Protein | <6% | USP |
| Ph (1%H2o Solution) | 4.0-7.0 | USP791 |
| Specific Rotation | - 20°~ -30° | USP781S |
| Residue On Ingition (Dry Base) | 20%-30% | USP281 |
| Organic Volatile Residual | NMT0.5% | USP467 |
| Sulfate | ≤0.24% | USP221 |
| Chloride | ≤0.5% | USP221 |
| Clarity (5%H2o Solution) | <0.35@420nm | USP38 |
| Electrophoretic Purity | NMT2.0% | USP726 |
| Limite of none specific disaccharides | ＜10% | Enzymatic HPLC |
| Heavy Metals | ≤10 PPM | ICP-MS |
| Total Plate Count | ≤1000cfu/g | USP2021 |
| Yeast & Mold | ≤100cfu/g | USP2021 |
| Salmonella | Absence | USP2022 |
| E.Coli | Absence | USP2022 |
| Staphylococcus Aureus | Absence | USP2022 |
| Particle Size | Customized according to your requirments | In House |
| Bulk Density | >0.55g/ml | In House |
1. Improve joint health: Chondroitin sulfate can reduce joint inflammation and pain, increase joint lubrication, help to protect articular cartilage, and delay the progression of joint degenerative diseases.
2. Regulation of blood lipids: Chondroitin sulfate can reduce triglyceride and cholesterol levels in the blood, and can help to prevent and improve cardiovascular diseases, such as atherosclerosis.
3. Promote wound healing: chondroitin sulfate can promote angiogenesis and cell proliferation around the wound, and accelerate wound healing.
4. Anti-tumor: Chondroitin sulfate can inhibit the growth and spread of tumor cells, and help to prevent and treat tumors.
5. Anti-inflammatory effect: Chondroitin sulfate has an anti-inflammatory effect, which can reduce nerve migraine, neuralgia and other inflammatory symptoms.
1. Medical field: Chondroitin sulfate can be used as health food or health medicine, can be used for the treatment of neuropathic pain, neurological migraine, joint pain, arthritis, scapular joint pain, abdominal surgery pain, etc. At the same time, chondroitin sulfate can also prevent and treat the auditory disorders caused by streptomycin and various noise caused by hearing difficulties, tinnitus, etc.
2. Cosmetic field: Chondroitin sulfate is also used in cosmetics. Is a pure natural moisturizer, skin conditioner, with a very good moisturizing ability.
3. Wound healing field: Chondroitin sulfate can be used as a healing agent for traumatic wounds, and some studies have shown that it also has a certain role in skin health and wound healing.
4. Food and nutritional supplements: It can be widely used as a nutritional ingredient in health food, infant formula food, etc. Chondroitin sulfate promotes bone growth and repair, and enhances bone density, and therefore is often used as a nutritional supplement for specific groups such as the elderly and athletes.
1.Production equipment: All equipment is electronically controlled automatically to make production more efficient, and it is equipped with special cleaning equipment to disinfect production equipment regularly.
2.Good control of the production link: we have professional technicians and electronic detection system for multiple monitoring. It can directly supervise and control each production link to ensure the efficiency of the production link.
3.Complete production workshop management system: the quality of our products must be guaranteed, so we attach great importance to the production environment. 4. Good storage conditions: we have an independent product storage workshop, products are unified systematic management.
1. Typical COA of our chondroitin sulfate is available for your specification checking purpose.
2. Techinical Data sheet of chondroitin sulfate is available for your review.
3. MSDS of chondroitin sulfate is available for your checking how to handle this material in your laboratory or in your production facility.
4. We are also able to provide Nutrition Fact of chondroitin sulfate for your checking.
5. We are ready to Supplier Questionaire form from your company.
6. Other qualification documents will be sent to you upon your requests.
Can I get some samples for testing?
Yes, we can arrange free samples, but please kindly pay for the freight cost. If you have a DHL account, we can send via your DHL account.
Does preshipment sample available?
Yes, we can arrange preshipment sample, tested OK, you can place the order.
What is your payment method?
T/T, and Paypal is prefered.
How can we make sure that the quality meets our requirments?
1. Typical Sample is available for your testing before placing the order.
2. Pre-shipment sample send to you before we ship the goods.
What's your MOQ?
Our MOQ is 1kg.
